Can you expect cyclists coming from the opposite direction on this road?

Why?

Below the D-3 one-way sign is an exemption plate showing a bicycle. Cyclists are therefore allowed to travel in both directions, so you should expect them to approach from ahead. The cycle lane visible on the left also indicates this arrangement.

§ 44 ust. 1 i 2 rozporządzenia w sprawie znaków i sygnałów drogowych